Lifespan changes: From wild type to Cp;Heph

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Genetic mutants with Cp, Heph alterations

    Names of genes are ordered alphabetically. For the order of interventions, please see the specific paper.
  • Diet

    ad libitum

  • Lifespan (days)


  • Lifespan comparisons

    Double mutant Cp(KO);Heph(sla) has a lifespan of 175.0 days, while single mutant Cp(KO) has a lifespan of 175.0 days.

  • Citation
    View abstract

    Zhao L et al., 2015, Cp/Heph mutant mice have iron-induced neurodegeneration diminished by deferiprone. J Neurochem. 135(5):958-74 PubMed 26303407 Click here to select all mutants from this PubMed ID in the graph

Search genes: Cp Heph
  • Entrez ID
  • Symbol
  • GenAge
  • MGI ID


  • Entrez ID
  • Symbol
  • GenAge
  • MGI ID


Orthologs of Cp;Heph in SynergyAge
Show in SynergyAge
Species Gene
Orthologs of Cp in SynergyAge
Show in SynergyAge
Species Gene
Orthologs of Heph in SynergyAge
Show in SynergyAge
Species Gene

SynergyAge database hosts high-quality, manually curated information about the synergistic and antagonistic lifespan effects of genetic interventions in model organisms, also allowing users to explore the longevity relationships between genes in a visual way.

Read more about SynergyAge database

How to cite us

If you would like to cite this database please use:

Bunu, G., Toren, D., Ion, C. et al. SynergyAge, a curated database for synergistic and antagonistic interactions of longevity-associated genes. Sci Data 7, 366 (2020). https://doi.org/10.1038/s41597-020-00710-z

Robi Tacutu, Ph.D.
Head: Systems Biology of Aging Group, Bioinformatics & Structural Biochemistry Department
Institute of Biochemistry, Ground floor
Splaiul Independentei 296, Bucharest, Romania

Group webpage: www.aging-research.group