Ripk3;Sod1

Lifespan changes: From wild type to Ripk3;Sod1

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Genetic mutants with Ripk3, Sod1 alterations

    Names of genes are ordered alphabetically. For the order of interventions, please see the specific paper.
  • Temperature °C

    20–22°C

  • Diet

    ad libitum

  • Lifespan (days)

    178.0

  • Lifespan comparisons

    Double mutant Ripk3(KO);SOD1(G93A) has a lifespan of 178.0 days, while single mutant SOD1(G93A) has a lifespan of 157.0 days.

  • Citation
    View abstract

    Dermentzaki G et al., 2019, Deletion of Ripk3 Prevents Motor Neuron Death In Vitro but not In Vivo. eNeuro. 6(1). pii: ENEURO PubMed 30815534 Click here to select all mutants from this PubMed ID in the graph

  • Temperature °C

    20–22°C

  • Diet

    ad libitum

  • Lifespan (days)

    170.0

  • Lifespan comparisons

    Double mutant Ripk3(KO);SOD1(G93A) has a lifespan of 170.0 days, while single mutant SOD1(G93A) has a lifespan of 170.0 days.

  • Citation
    View abstract

    Dermentzaki G et al., 2019, Deletion of Ripk3 Prevents Motor Neuron Death In Vitro but not In Vivo. eNeuro. 6(1). pii: ENEURO PubMed 30815534 Click here to select all mutants from this PubMed ID in the graph

Search genes: Ripk3 Sod1
  • Entrez ID
  • Symbol
  • GenAge
  • MGI ID

receptor-interacting serine-threonine kinase 3

  • Entrez ID
  • Symbol
  • GenAge
  • MGI ID

superoxide dismutase 1, soluble

Orthologs of Ripk3;Sod1 in SynergyAge
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Species Gene
Orthologs of Ripk3 in SynergyAge
Show in SynergyAge
Species Gene
Orthologs of Sod1 in SynergyAge
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Species Gene
Caenorhabditis elegans sod-1
Caenorhabditis elegans sod-5
Drosophila melanogaster Sod1
About

SynergyAge database hosts high-quality, manually curated information about the synergistic and antagonistic lifespan effects of genetic interventions in model organisms, also allowing users to explore the longevity relationships between genes in a visual way.

Read more about SynergyAge database

How to cite us

If you would like to cite this database please use:

Bunu, G., Toren, D., Ion, C. et al. SynergyAge, a curated database for synergistic and antagonistic interactions of longevity-associated genes. Sci Data 7, 366 (2020). https://doi.org/10.1038/s41597-020-00710-z

Contact
Robi Tacutu, Ph.D.
Head: Systems Biology of Aging Group, Bioinformatics & Structural Biochemistry Department
Institute of Biochemistry, Ground floor
Splaiul Independentei 296, Bucharest, Romania
Email:

Group webpage: www.aging-research.group