Mobr;Sod1

Lifespan changes: From wild type to Mobr;Sod1

There is no network for this step.
Fullscreen mode
Hide graph
Legend

Genetic mutants with Mobr, Sod1 alterations

    Names of genes are ordered alphabetically. For the order of interventions, please see the specific paper.
  • Lifespan (days)

    128.0

  • Phenotype

    Increased life span of Mobr/SOD1G86R double mutants. This difference represents a 9% increase in life span for the copper-deficient double-mutant Mobr/SOD1G86R compared with the nondeficient single-mutant SOD1G86R mice.

  • Lifespan comparisons

    Double mutant Mobr(KO);SOD1(G86R) has a lifespan of 128.0 days, while single mutant SOD1(G86R) has a lifespan of 118.0 days.

  • Citation
    View abstract

    Kiaei M et al., 2004, Genetically decreased spinal cord copper concentration prolongs life in a transgenic mouse model of amyotrophic lateral sclerosis. J Neurosci. 24(36):7945-50 PubMed 15356208 Click here to select all mutants from this PubMed ID in the graph

Search genes: Mobr Sod1
  • Symbol
  • GenAge

No gene information for Mobr


  • Entrez ID
  • Symbol
  • GenAge
  • MGI ID

superoxide dismutase 1, soluble


Orthologs of Mobr;Sod1 in SynergyAge
Show in SynergyAge
Species Gene
Orthologs of Mobr in SynergyAge
Show in SynergyAge
Species Gene
Orthologs of Sod1 in SynergyAge
Show in SynergyAge
Species Gene
Caenorhabditis elegans sod-1
Caenorhabditis elegans sod-5
Drosophila melanogaster Sod1
About

SynergyAge database hosts high-quality, manually curated information about the synergistic and antagonistic lifespan effects of genetic interventions in model organisms, also allowing users to explore the longevity relationships between genes in a visual way.

Read more about SynergyAge database

How to cite us

If you would like to cite this database please use:

Bunu, G., Toren, D., Ion, C. et al. SynergyAge, a curated database for synergistic and antagonistic interactions of longevity-associated genes. Sci Data 7, 366 (2020). https://doi.org/10.1038/s41597-020-00710-z

Contact
Robi Tacutu, Ph.D.
Head: Systems Biology of Aging Group, Bioinformatics & Structural Biochemistry Department
Institute of Biochemistry, Ground floor
Splaiul Independentei 296, Bucharest, Romania
Email:

Group webpage: www.aging-research.group