Lifespan changes: From wild type to Mobr;Sod1

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Genetic mutants with Mobr, Sod1 alterations

    Names of genes are ordered alphabetically. For the order of interventions, please see the specific paper.
  • Lifespan (days)


  • Phenotype

    Increased life span of Mobr/SOD1G86R double mutants. This difference represents a 9% increase in life span for the copper-deficient double-mutant Mobr/SOD1G86R compared with the nondeficient single-mutant SOD1G86R mice.

  • Lifespan comparisons

    Double mutant Mobr(KO);SOD1(G86R) has a lifespan of 128.0 days, while single mutant SOD1(G86R) has a lifespan of 118.0 days.

  • Citation
    View abstract

    Kiaei M et al., 2004, Genetically decreased spinal cord copper concentration prolongs life in a transgenic mouse model of amyotrophic lateral sclerosis. J Neurosci. 24(36):7945-50 PubMed 15356208 Click here to select all mutants from this PubMed ID in the graph

Search genes: Mobr Sod1
  • Symbol
  • GenAge

No gene information for Mobr

  • Entrez ID
  • Symbol
  • GenAge
  • MGI ID

superoxide dismutase 1, soluble

Orthologs of Mobr;Sod1 in SynergyAge
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Species Gene
Orthologs of Mobr in SynergyAge
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Species Gene
Orthologs of Sod1 in SynergyAge
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Species Gene
Caenorhabditis elegans sod-1
Caenorhabditis elegans sod-5
Drosophila melanogaster Sod1

SynergyAge database hosts high-quality, manually curated information about the synergistic and antagonistic lifespan effects of genetic interventions in model organisms, also allowing users to explore the longevity relationships between genes in a visual way.

Read more about SynergyAge database

How to cite us

If you would like to cite this database please use:

Bunu, G., Toren, D., Ion, C. et al. SynergyAge, a curated database for synergistic and antagonistic interactions of longevity-associated genes. Sci Data 7, 366 (2020).

Robi Tacutu, Ph.D.
Head: Systems Biology of Aging Group, Bioinformatics & Structural Biochemistry Department
Institute of Biochemistry, Ground floor
Splaiul Independentei 296, Bucharest, Romania

Group webpage: