Lifespan changes: From wild type to Hgf;Sod1
295.0
Double mutant Hgf(OE);Sod1(G93A) has a lifespan of 295.0 days, while single mutant Sod1(G93A) has a lifespan of 250.0 days.
Sun W et al., 2002, Overexpression of HGF retards disease progression and prolongs life span in a transgenic mouse model of ALS. J Neurosci. 22(15):6537-48 12151533 Click here to select all mutants from this PubMed ID in the graph
Show in SynergyAge | |
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Species | Gene |
Show in SynergyAge | |
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Species | Gene |
SynergyAge database hosts high-quality, manually curated information about the synergistic and antagonistic lifespan effects of genetic interventions in model organisms, also allowing users to explore the longevity relationships between genes in a visual way.
If you would like to cite this database please use:
Bunu, G., Toren, D., Ion, C. et al. SynergyAge, a curated database for synergistic and antagonistic interactions of longevity-associated genes. Sci Data 7, 366 (2020). https://doi.org/10.1038/s41597-020-00710-z
Group webpage: www.aging-research.group