Lifespan changes: From wild type to Pi3K92E / From Pi3K92E to multiple mutants DF = decrease in function; IF = increase in function

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Genetic mutants with Pi3K92E alterations

  • Strain


  • Temperature °C


  • Diet

    sugar/yeast medium

  • Lifespan (days)


  • Lifespan change (compared to wild type)


  • Lifespan comparisons

    Single mutant Pi3K92E(DF) has a lifespan of 80.0 days, while wild type has a lifespan of 75.0 days.

  • Citation
    View abstract

    Slack C et al., 2011, dFOXO-independent effects of reduced insulin-like signaling in Drosophila. Aging Cell. 10(5):735-48 PubMed 21443682 Click here to select all mutants from this PubMed ID in the graph

Search genes: Pi3K92E
  • Entrez ID
  • Symbol
  • GenAge
  • FlyBase ID


Locus: Dmel_CG4141

Orthologs of Pi3K92E in SynergyAge
Show in SynergyAge
Species Gene
Caenorhabditis elegans age-1

SynergyAge database hosts high-quality, manually curated information about the synergistic and antagonistic lifespan effects of genetic interventions in model organisms, also allowing users to explore the longevity relationships between genes in a visual way.

Read more about SynergyAge database

How to cite us

If you would like to cite this database please use:

Bunu, G., Toren, D., Ion, C. et al. SynergyAge, a curated database for synergistic and antagonistic interactions of longevity-associated genes. Sci Data 7, 366 (2020). https://doi.org/10.1038/s41597-020-00710-z

Robi Tacutu, Ph.D.
Head: Systems Biology of Aging Group, Bioinformatics & Structural Biochemistry Department
Institute of Biochemistry, Ground floor
Splaiul Independentei 296, Bucharest, Romania

Group webpage: www.aging-research.group