p38b

Lifespan changes: From wild type to p38b / From p38b to multiple mutants DF = decrease in function; IF = increase in function

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Genetic mutants with p38b alterations

  • Strain

    p38b[?45]

  • Temperature °C

    25

  • Diet

    Standard Drosophila culture medium

  • Lifespan (days)

    19.0

  • Lifespan change (compared to wild type)

    -61.22%

  • Lifespan comparisons

    Single mutant p38b(df) has a lifespan of 19.0 days, while wild type has a lifespan of 49.0 days.

  • Citation
    View abstract

    Vrailas-Mortimer A et al., 2011, A muscle-specific p38 MAPK/Mef2/MnSOD pathway regulates stress, motor function, and life span in Drosophila. Dev Cell. 21(4):783-95 PubMed 22014527 Click here to select all mutants from this PubMed ID in the graph

  • Strain

    p38b[?45]

  • Temperature °C

    25

  • Diet

    Standard Drosophila culture medium

  • Lifespan (days)

    68.0

  • Lifespan change (compared to wild type)

    38.78%

  • Lifespan comparisons

    Single mutant p38b(df) has a lifespan of 68.0 days, while wild type has a lifespan of 49.0 days.

  • Citation
    View abstract

    Vrailas-Mortimer A et al., 2011, A muscle-specific p38 MAPK/Mef2/MnSOD pathway regulates stress, motor function, and life span in Drosophila. Dev Cell. 21(4):783-95 PubMed 22014527 Click here to select all mutants from this PubMed ID in the graph

Search genes: p38b
  • Entrez ID
  • Symbol
  • GenAge
  • FlyBase ID

p38b MAP kinase


Locus: Dmel_CG7393


Orthologs of p38b in SynergyAge
Show in SynergyAge
Species Gene
Caenorhabditis elegans pmk-1
About

SynergyAge database hosts high-quality, manually curated information about the synergistic and antagonistic lifespan effects of genetic interventions in model organisms, also allowing users to explore the longevity relationships between genes in a visual way.

Read more about SynergyAge database

How to cite us

If you would like to cite this database please use:

Bunu, G., Toren, D., Ion, C. et al. SynergyAge, a curated database for synergistic and antagonistic interactions of longevity-associated genes. Sci Data 7, 366 (2020). https://doi.org/10.1038/s41597-020-00710-z

Contact
Robi Tacutu, Ph.D.
Head: Systems Biology of Aging Group, Bioinformatics & Structural Biochemistry Department
Institute of Biochemistry, Ground floor
Splaiul Independentei 296, Bucharest, Romania
Email:

Group webpage: www.aging-research.group