Roundworm

Roundworm

Caenorhabditis elegans, the most popular nematode.

Legend
Fullscreen mode
VR mode
Hide graph
First page Next Last page
All mutants (1727 results, without single mutants) Mutant type No. experiments Change in average lifespan   Epistasis
aak-1;aak-2 Double mutant 1 -15.12%  
aak-1;aak-2;frh-1 Triple mutant 1 4.07%  
aak-1;frh-1 Double mutant 1 25.00%  
aak-2;atp-3 Double mutant 2 -40.12% .. -33.72%  
aak-2;cco-1 Double mutant 2 40.70% .. 48.26%  
aak-2;chc-1 Double mutant 1 -13.30%  
aak-2;cyc-2.1 Double mutant 2 -20.00% .. -15.87%  
aak-2;daf-16 Double mutant 2 -44.33% .. -27.00%  
aak-2;daf-16;daf-2 Triple mutant 1 -35.37%  
aak-2;daf-2 Double mutant 7 -14.00% .. 75.78%  
aak-2;daf-2;rsks-1 Triple mutant 7 73.85% .. 175.89%  
aak-2;daf-9 Double mutant 1 10.81%  
aak-2;fasn-1 Double mutant 1 -11.82%  
aak-2;frh-1 Double mutant 2 -5.23% .. 34.30%  
aak-2;ifg-1 Double mutant 1 7.88%  
aak-2;igf-1 Double mutant 1 -12.18%  
aak-2;isp-1 Double mutant 2 31.98% .. 125.58%  
aak-2;let-711 Double mutant 1 -14.78%  
aak-2;mdt-15 Double mutant 1 -39.90%  
aak-2;nmur-1 Double mutant 1 23.21%  
aak-2;nuo-2 Double mutant 2 22.09% .. 30.23%  
aak-2;rsks-1 Double mutant 5 -30.77% .. 1.13%  
aak-2;sca-1 Double mutant 1 -10.84%  
aak-2;sod-1 Double mutant 2 -45.48% .. -184.47% [est.]
aak-2;unc-70 Double mutant 1 -14.78%  
aak-2;xbp-1 Double mutant 3 -20.00% .. 41.45%  
aakb-1;daf-2 Double mutant 5 66.89% .. 101.48%  
aakg-1;daf-2;rff-3 Triple mutant 4 -32.13% .. -130.35% [est.]
aakg-2;daf-2;rff-3 Triple mutant 4 -24.88% .. -100.94% [est.]
aakg-3;daf-2;rff-3 Triple mutant 4 -28.07% .. -113.88% [est.]
aakg-4;aakg-5 Double mutant 2 7.07% .. 25.77%  
aakg-4;aakg-5;daf-2 Triple mutant 2 98.99%  
aakg-4;daf-2 Double mutant 11 61.76% .. 115.32%  
aakg-4;daf-2;rff-3 Triple mutant 6 -42.0% .. -170.35% [est.]
aakg-4;daf-2;rsks-1 Triple mutant 2 90.63% .. 91.18%  
aakg-4;rrf-3 Double mutant 4 -70.13% .. -284.47% [est.]
aakg-4;rsks-1 Double mutant 2 3.12% .. 10.29%  
aakg-5;daf-2 Double mutant 3 74.23% .. 104.04%  
aakg-5;daf-2;rff-3 Triple mutant 5 -48.38% .. -196.24% [est.]
aakg-5;rrf-3 Double mutant 1 -65.2% .. 41.18% [est.]
aap-1;asm-3 Double mutant 1 48.87% .. 503.88% [est.]
aat-2;daf-16;rrf-3 Triple mutant 1 -23.27%  
abu-11;daf-2 Double mutant 4 40.20% .. 123.04%  
acdh-13;daf-16;rrf-3 Triple mutant 1 12.19%  
aco-2;daf-2 Double mutant 2 35.06% .. 142.24% [est.]
acs-5;daf-16;rrf-3 Triple mutant 1 -13.73%  
ada-2;daf-16;daf-2 Triple mutant 1 -41.50%  
ada-2;daf-2 Double mutant 1 95.92%  
age-1;akt-1;sqt-1 Triple mutant 1 83.33%  
age-1;asm-3 Double mutant 1 258.76%  
First page Next Last page
About

SynergyAge database hosts high-quality, manually curated information about the synergistic and antagonistic lifespan effects of genetic interventions in model organisms, also allowing users to explore the longevity relationships between genes in a visual way.

Read more about SynergyAge database

How to cite us

If you would like to cite this database please use:

Bunu, G., Toren, D., Ion, C. et al. SynergyAge, a curated database for synergistic and antagonistic interactions of longevity-associated genes. Sci Data 7, 366 (2020). https://doi.org/10.1038/s41597-020-00710-z

Contact
Robi Tacutu, Ph.D.
Head: Systems Biology of Aging Group, Bioinformatics & Structural Biochemistry Department
Institute of Biochemistry, Ground floor
Splaiul Independentei 296, Bucharest, Romania
Email:

Group webpage: www.aging-research.group